Medical

Antimicrobial Resistance in the 21st Century | ,

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This comprehensive, up-to-date volume defines the issues and offers potential solutions to the challenges of antimicrobial resistance. The chapter authors are leading international experts on antimicrobial resistance among a variety of bacteria, viruses including HIV and herpes, parasites and fungi. The chapters explore the molecular mechanisms of drug resistance, the immunology and epidemiology of resistance strains, clinical implications and implications on research and lack thereof, and prevention and future directions..

Philosophy

Ethics and Drug Resistance: Collective Responsibility for Global Public Health | Euzebiusz Jamrozik,Michael Selgelid

Ethics and Drug Resistance: Collective Responsibility for Global Public Health Pdf/ePub eBook Ethics and Drug Resistance: Collective Responsibility for Global Public Health Pdf ebook download. Number Downloads: 704 | Ebook Reads: 704 | File: Ethics and Drug Resistance: Collective Responsibility for Global Public Health.pdf/epub | ISBNCode: 3030278743

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This Open Access volume provides in-depth analysis of the wide range of ethical issues associated with drug-resistant infectious diseases. Antimicrobial resistance (AMR) is widely recognized to be one of the greatest threats to global public health in coming decades; and it has thus become a major topic of discussion among leading bioethicists and scholars from related disciplines including economics, epidemiology, law, and political theory. Topics covered in this volume include responsible use of antimicrobials; control of multi-resistant hospital-acquired infections; privacy and data collection; antibiotic use in childhood and at the end of life; agricultural and veterinary sources of resistance; resistant HIV, tuberculosis, and malaria; mandatory treatment; and trade-offs between current and future generations. As the first book focused on ethical issues associated with drug resistance, it makes a timely contribution to debates regarding practice and policy that are of crucial importance to global public health in the 21st century..

Political Science

Routledge Handbook of Nuclear Proliferation and Policy | Joseph F. Pilat,Nathan E. Busch

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This new Handbook is a comprehensive examination of the rich and complex issues of nuclear proliferation in the early 21st century. The future of the decades-long effort to prevent the further spread of weapons of mass destruction is at a crossroads today. If international nonproliferation efforts are to be successful, an integrated, multi-tiered response will almost certainly be necessary. A serious, thorough, and clear-eyed examination of the range of threats, challenges, and opportunities facing the international community is a necessary first step. This Handbook, which presents the most up-to-date analysis and policy recommendations on these critical issues by recognized, leading scholars in the field, intends to provide such an examination. The volume is divided into three major parts: Part I presents detailed threat assessments of proliferation risks across the globe, including specific regions and countries. Part II explains the various tools developed by the international community to address these proliferation threats. Part III addresses the proliferation risks and political challenges arising from nuclear energy production, including potential proliferation by aspiring states and nonstate groups. This Handbook will be of great interest to students and practitioners of nuclear proliferation, arms control, global governance, diplomacy, and global security and IR general..

Law

International Farm Animal, Wildlife and Food Safety Law | Gabriela Steier,Kiran K. Patel

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This volume is an inspiring and breakthrough piece of academic scholarship and the first of its kind featuring a comprehensive reader-friendly approach to teach the intricacies of the various aspects of international farm animal, wildlife conservation, food safety and environmental protection law. The selected focus areas are grouped in sections, such as agrobiodiversity, fishing and aquaculture, pollinators and pesticides, soil management, industrial animal production and transportation, and international food trade. Farm animal welfare, environmental protection, biodiversity conservation, and food safety are the core of the selected chapters. Every chapter provides real-world examples to make the complex field easy to understand. With its systematic approach, this book is devoted to anyone interested in the subject, becomes a valuable resource for professionals working in food regulation, and provides a solid foundation for courses and master’s programs in animal law, environmental policy, food and agriculture law, and regulation of these subjects around the world. Through its emphasis on sustainable food production, this work offers a cutting-edge selection of evolving topics at the heart of the pertinent discourse. As one of its highlights, this books also provides “Tools for Change,” a unique compilation and analysis of laws from the major farm animal product trading nations. With these tools, practitioners, advocates, policy makers and other state-holders are equipped with information to start work toward improving farm animal welfare, wildlife conservation, and food safety through the use of law and policy..

Medical

Antimicrobials | Flavia Marinelli,Olga Genilloud

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Reports on the emergence and prevalence of resistant bacterial infections in hospitals and communities raise concerns that we may soon no longer be able to rely on antibiotics as a way to control infectious diseases. Effective medical care would require the constant introduction of novel antibiotics to keep up in the “arms race” with resistant pathogens. This book closely examines the latest developments in the field of antibacterial research and development. It starts with an overview of the growing prevalence of resistant Gram-positive and Gram-negative pathogens, including their various resistance mechanisms, prevalence, risk factors and therapeutic options. The focus then shifts to a comprehensive description of all major chemical classes with antibacterial properties, their chemistry, mode of action, and the generation of analogs; information that provides the basis for the design of improved molecules to defeat microbial infections and combat the emerging resistances. In closing, recently developed compounds already in clinical use, those in preclinical or first clinical studies, and a number of promising targets to be exploited in the discovery stage are discussed..

Medical

Antimicrobial Resistance in Agriculture | Indranil Samanta,Samiran Bandyopadhyay

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Antimicrobial Resistance in Agriculture: Perspective, Policy and Mitigation is a valuable industrial resource that addresses complex, multi-factorial topics regarding farm, wild, companion animals, fish, and how the environment plays an important role in amplification and transmission of resistant bugs into the human food chain. Information of phenotypical and genotypical properties of each bacterial genus associated with antimicrobial resistance, transmission dynamics from different reservoirs (food animals, poultry, fishes) and control measures with alternative therapy, such as phytobiotics and nanomaterials are provided. Researchers, scientists and practitioners will find this an essential resource on the judicial use of antibiotics in animals and humans. Explores all the genera of livestock and fish originated pathogenic bacteria associated with antimicrobial resistance Presents cutting-edge research on epigenetics, nanotechnology and intervention technologies Discusses transmission dynamics of resistance gene pools from different reservoirs, including food animals, poultry, fishes and the environment.

Medical

Collaborative Antimicrobial Stewardship,An Issue of Infectious Disease Clinics of North America ,E-Book | Shaefer Spires,Elizabeth Dodds Ashley

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Together with Consulting Editor Dr. Helen Boucher, Drs. Elizabeth Dodds-Ashley and S. Schaefer Spires have put together a unique issue that discusses collaborative antimicrobial stewardship. Expert authors have contributed clinical review articles on the following topics: Collaborative Antimicrobial Stewardship for Hospitalists; Collaborative Antimicrobial Stewardship in Microbiology; Collaborative Antimicrobial Stewardship in Nursing; Infection Prevention in Collaborative Antimicrobial Stewardship; Collaborative Antimicrobial Stewardship in the Health Department; Collaborative Antimicrobial Stewardship in Primary Care; Collaborative Antimicrobial Stewardship in Health System Administration; Collaborative Antimicrobial Stewardship for Surgeons; Collaborative Antimicrobial Stewardship in the Emergency Department; and Collaborative Antimicrobial Stewardship in Long-Term Care Facilities. Readers will come away with the information they need to collaborate across disciplines to improve the incidence of antibiotic resistance in their healthcare settings..

Medical

Handbook of Child and Adolescent Tuberculosis | Jeffrey R. Starke,Peter R. Donald

Handbook of Child and Adolescent Tuberculosis Pdf/ePub eBook Handbook of Child and Adolescent Tuberculosis Pdf ebook download. Number Downloads: 1367 | Ebook Reads: 1367 | File: Handbook of Child and Adolescent Tuberculosis.pdf/epub | ISBNCode: 0190220910

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Tuberculosis remains one of the most prevalent, deadly, and underdiagnosed infectious diseases in the world. In children, this burden is doubly problematic because of the disease's unique clinical characteristics and its need for special public health and diagnostic techniques. After decades of relative inattention to these factors, childhood tuberculosis has now grown into an important area of competency for child health programs in low-burden areas, including the United States. The Handbook of Child and Adolescent Tuberculosis is a state of the art clinical reference written and edited by the world's leading experts in childhood tuberculosis. It offers clinicians in any geography or setting practical, evidence-based advice on all aspects of the disease, including its natural history, epidemiology, presentation, treatment, and prevention -- all in a format that synthesizes literature with the clinical experience of the leading authorities in this challenging field. As the need for childhood tuberculosis services in child health programs grows, this handbook provides a new benchmark for practitioners and trainees in pediatrics, infectious disease, pulmonary medicine, and public health to better understand this persisting and difficult disease..

Technology & Engineering

Integration of Insect-Resistant Genetically Modified Crops within IPM Programs | Jörg Romeis,Anthony M. Shelton,George Kennedy

Integration of Insect-Resistant Genetically Modified Crops within IPM Programs Pdf/ePub eBook Integration of Insect-Resistant Genetically Modified Crops within IPM Programs Pdf ebook download. Number Downloads: 393 | Ebook Reads: 393 | File: Integration of Insect-Resistant Genetically Modified Crops within IPM Programs.pdf/epub | ISBNCode: 1402083734

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Insect pests remain one of the main constraints to food and fiber production worldwide despite farmers deploying a range of techniques to protect their crops. Modern pest control is guided by the principles of integrated pest management (IPM) with pest resistant germplasm being an important part of the foundation. Since 1996, when the first genetically modified (GM) insect-resistant maize variety was commercialized in the USA, the area planted to insect-resistant GM varieties has grown dramatically, representing the fastest adoption rate of any agricultural technology in human history. The goal of our book is to provide an overview on the role insect-resistant GM plants play in different crop systems worldwide. We hope that the book will contribute to a more rational debate about the role GM crops can play in IPM for food and fiber production..

Philosophy

On Resistance | Howard Caygill

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No word is more central to the contemporary political imagination and action than 'resistance'. In its various manifestations - from the armed guerrilla to Gandhian mass pacifist protest, from Wikileaks and the Arab Spring to the global eruption and violent repression of the Occupy movement - concepts of resistance are becoming ubiquitous and urgent. In this book, Howard Caygill conducts the first ever systematic analysis of 'resistance': as a means of defying political oppression, in its relationship with military violence and its cultural representation. Beginning with the militaristic doctrine of Clausewitz and the evolution of a new model of guerrilla warfare to resist the forces of Napoleonic France, On Resistance elucidates and critiques the contributions of seminal resistant thinkers from Marx and Nietzsche to Mao, Gandhi, Sartre and Fanon to identify continuities of resistance and rebellion from the Paris Commune to the Greenham Women's Peace Camp. Employing a threefold line of inquiry, Caygill exposes the persistent discourses through which resistance has been framed in terms of force, violence, consciousness and subjectivity to evolve a critique of resistance. Tracing the features of resistance, its strategies, character and habitual forms throughout modern world history Caygill identifies the typological consistencies which make up resistance. Finally, by teasing out the conceptual nuances of resistance and its affinities to concepts of repression, reform and revolution, Caygill reflects upon contemporary manifestations of resistance to identify whether the 21st century is evolving new understandings of protest and struggle..

Technology & Engineering

Comprehensive Materials Processing | ,

Comprehensive Materials Processing Pdf/ePub eBook Comprehensive Materials Processing Pdf ebook download. Number Downloads: 909 | Ebook Reads: 909 | File: Comprehensive Materials Processing.pdf/epub | ISBNCode: 0080965334

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Comprehensive Materials Processing provides students and professionals with a one-stop resource consolidating and enhancing the literature of the materials processing and manufacturing universe. It provides authoritative analysis of all processes, technologies, and techniques for converting industrial materials from a raw state into finished parts or products. Assisting scientists and engineers in the selection, design, and use of materials, whether in the lab or in industry, it matches the adaptive complexity of emergent materials and processing technologies. Extensive traditional article-level academic discussion of core theories and applications is supplemented by applied case studies and advanced multimedia features. Coverage encompasses the general categories of solidification, powder, deposition, and deformation processing, and includes discussion on plant and tool design, analysis and characterization of processing techniques, high-temperatures studies, and the influence of process scale on component characteristics and behavior. Authored and reviewed by world-class academic and industrial specialists in each subject field Practical tools such as integrated case studies, user-defined process schemata, and multimedia modeling and functionality Maximizes research efficiency by collating the most important and established information in one place with integrated applets linking to relevant outside sources.

Medical

International Encyclopedia of Public Health | William C Cockerham

International Encyclopedia of Public Health Pdf/ePub eBook International Encyclopedia of Public Health Pdf ebook download. Number Downloads: 827 | Ebook Reads: 827 | File: International Encyclopedia of Public Health.pdf/epub | ISBNCode: 0128037083

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International Encyclopedia of Public Health, Second Edition is an authoritative and comprehensive guide to the major issues, challenges, methods, and approaches of global public health. Taking a multidisciplinary approach, this new edition combines complementary scientific fields of inquiry, linking biomedical research with the social and life sciences to address the three major themes of public health research, disease, health processes, and disciplines. This book helps readers solve real-world problems in global and local health through a multidisciplinary and comprehensive approach. Covering all dimensions of the field, from the details of specific diseases, to the organization of social insurance agencies, the articles included cover the fundamental research areas of health promotion, economics, and epidemiology, as well as specific diseases, such as cancer, cardiovascular diseases, diabetes, and reproductive health. Additional articles on the history of public health, global issues, research priorities, and health and human rights make this work an indispensable resource for students, health researchers, and practitioners alike. Provides the most comprehensive, high-level, internationally focused reference work available on public health Presents an invaluable resource for both researchers familiar with the field and non-experts requiring easy-to-find, relevant, global information and a greater understanding of the wider issues Contains interdisciplinary coverage across all aspects of public health Incorporates biomedical and health social science issues and perspectives Includes an international focus with contributions from global domain experts, providing a complete picture of public health issues.

Medical

Antibiotics | Claudio O. Gualerzi,Letizia Brandi,Attilio Fabbretti,Cynthia L. Pon

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Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic resistance, this reference systematically covers currently known antibiotic classes, their molecular mechanisms and the targets on which they act. Novel targets such as cell signaling networks, riboswitches and bacterial chaperones are covered here, alongside the latest information on the molecular mechanisms of current blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for anyone involved in the development and therapeutic application of novel antibiotics..

,

Public Playground Safety Handbook | ,

Public Playground Safety Handbook Pdf/ePub eBook Public Playground Safety Handbook Pdf ebook download. Number Downloads: 583 | Ebook Reads: 583 | File: Public Playground Safety Handbook.pdf/epub | ISBNCode: 1437981828

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Medical

Pathways To Global Health: Case Studies In Global Health Diplomacy - | Matlin Stephen,Kickbusch Ilona

Pathways To Global Health: Case Studies In Global Health Diplomacy - Pdf/ePub eBook Pathways To Global Health: Case Studies In Global Health Diplomacy - Pdf ebook download. Number Downloads: 1694 | Ebook Reads: 1694 | File: Pathways To Global Health: Case Studies In Global Health Diplomacy -.pdf/epub | ISBNCode: 9813144041

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Following the publication of Negotiating and Navigating Global Health: Case Studies in Global Health Diplomacy Editor Ellen Rosskam and Ilona Kickbusch, this second volume of case studies will complement the first volume and extends its scope. The new book focuses on health diplomacy negotiations, in Geneva and elsewhere, that have involved WHO or that have substantial implications for the work of WHO. Each of the chapters provides a detailed account of a particular example of global health negotiation, concerning hard and soft law instruments but also addressing the full range of health issues — reaching from issues of research and development, polio eradication, NCDs and plain packaging, to the post-2015 process, the WHO reform and non-state involvement. The book therefore captures a wide-range of experiences of distinguished diplomats, academics and senior practitioners. The contributions to the book are written by negotiators and academics and thus, will provide a unique angle and a tool of reflection for a broad audience. In particular, it will be of interest not only to the academic community and students, but also to policy-makers and diplomats. The case studies will allow for learning on how negotiations work in a complex policy environment. The focus on WHO will explore how a major international organization engages in global health diplomacy and on the implications that health-related diplomacy taking place in a variety of settings has for its work. As such, the book is an important contribution to the growing field of global health diplomacy and to the debate about the role of WHO in the 21str century..

Technology & Engineering

National Summit on Strategies to Manage Herbicide-Resistant Weeds | National Research Council,Division on Earth and Life Studies,Board on Agriculture and Natural Resources,Planning Committee for a National Summit on Strategies to Manage Herbicide-Resistant Weeds

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National Summit on Strategies to Manage Herbicide-Resistant Weeds - National Research Council,Division on Earth and Life Studies,Board on Agriculture and Natural Resources,Planning Committee for a National Summit on Strategies to Manage Herbicide-Resistant Weeds Preview:

Preserving the efficacy of herbicides and of herbicide-resistance technology depends on awareness of the increasing resistance of weeds to herbicides used in agriculture and coordinated action to address the problem by individuals at the farm level and beyond. This summit served as a venue to bring the attention of important stakeholders to the issue and as an opportunity for experts from diverse disciplines to strategize in a coordinated way to address herbicide-resistant weeds. In convening stakeholders for this event, participants took a step toward a recommendation from the 2010 National Research Council report The Impact of Genetically Engineered Crops on Farm Sustainability in the United States that federal and state government agencies, private-sector technology developers, universities, farmer organizations, and other relevant stakeholders collaborate to document emerging weed-resistance problems and to develop cost-effective resistance-management programs and practices that preserve effective weed control. The summit provided the opportunity for stakeholders to explore the scientific basis of the emergence of herbicide resistance and to consider different perspectives on both opportunities and barriers to overcoming the problem of herbicide-resistant weeds. National Summit on Strategies to Manage Herbicide-Resistant Weeds contains a brief synopsis of key points made by each speaker at the summit..

Health & Fitness

The Essential Oils Hormone Solution | Dr. Mariza Snyder

The Essential Oils Hormone Solution Pdf/ePub eBook The Essential Oils Hormone Solution Pdf ebook download. Number Downloads: 1251 | Ebook Reads: 1251 | File: The Essential Oils Hormone Solution.pdf/epub | ISBNCode: 1635653169

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NATIONAL BESTSELLER • Have your hormones been hijacked? Reset your hormonal health in 14 days with essential oils. “An effective, easy-to-follow plan to balance hormones and become more energized.”–Amy Myers, M.D., New York Times bestselling author of The Autoimmune Solution Do you feel energy-depleted and irritable, unable to sleep, stay focused, or lose weight? You may have attributed these symptoms to the natural hormonal fluctuations that occur with age. But behind the scenes, there are a host of pesky culprits wreaking havoc on your hormonal health: chronic stress, air pollution, chemical-laden foods and cleaning supplies, and the synthetic estrogens in personal care products. Women of all ages are left vulnerable to the consequences, suffering from unnecessary hormonal imbalance and frustrating symptoms that are often dismissed by their doctors. Dr. Mariza Snyder is here to help put you back in control of your health. In The Essential Oils Hormone Solution, you will learn how to heal hormonal chaos and revitalize the body from the inside out with the support of high-quality essential oils. You’ll learn how essential oils work on a cellular level to mitigate the toxic loads we carry, and how to use essential oils to reduce cravings, get deep, restful sleep, ease stress, improve mood, banish the worst symptoms of PMS, regain focus and concentration, boost libido, and increase energy. Featuring a 14-day plan to jumpstart your hormonal health, with over 100 essential oil blends, daily self-care rituals, and delicious, easy-to-prepare recipes, you’ll discover how to reset your body and pave the way for improved hormonal health, without taking hormones..

Medical

Food Microbiology | Michael P. Doyle,Francisco Diez-Gonzalez,Colin Hill

Food Microbiology Pdf/ePub eBook Food Microbiology Pdf ebook download. Number Downloads: 1038 | Ebook Reads: 1038 | File: Food Microbiology.pdf/epub | ISBNCode: 1555819974

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Since its introduction in 1997, the purpose of Food Microbiology: Fundamentals and Frontiers has been to serve as an advanced reference that explores the breadth and depth of food microbiology. Thoroughly updated, the new Fifth Edition adds coverage of the ever-expanding tool chest of new and extraordinary molecular methods to address many of the roles that microorganisms play in the production, preservation, and safety of foods. Sections in this valuable reference cover material of special significance to food microbiology such as: stress response mechanisms, spores, and the use of microbiological criteria and indicator organisms commodity-oriented discussion of types of microbial food spoilage and approaches for their control the major foodborne pathogens, including diseases, virulence mechanisms, control measures, and up-to-date details on molecular biology techniques state-of-the-science information on food preservation approaches, including natural antimicrobials and the use of bacteriophages in controlling foodborne pathogens beneficial microbes used in food fermentations and to promote human and animal health updated chapters on current topics such as antimicrobial resistance, predictive microbiology, and risk assessment This respected reference provides up-to-the-minute scientific and technical insights into food production and safety, readily available in one convenient source..

Business & Economics

Causal Analytics for Applied Risk Analysis | Louis Anthony Cox Jr.,Douglas A. Popken,Richard X. Sun

Causal Analytics for Applied Risk Analysis Pdf/ePub eBook Causal Analytics for Applied Risk Analysis Pdf ebook download. Number Downloads: 1790 | Ebook Reads: 1790 | File: Causal Analytics for Applied Risk Analysis.pdf/epub | ISBNCode: 3319782428

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Causal analytics methods can revolutionize the use of data to make effective decisions by revealing how different choices affect probabilities of various outcomes. This book presents and illustrates models, algorithms, principles, and software for deriving causal models from data and for using them to optimize decisions with uncertain outcomes. It discusses how to describe and summarize situations; detect changes; evaluate effects of policies or interventions; learn what works best under different conditions; predict values of as-yet unobserved quantities from available data; and identify the most likely explanations for observed outcomes, including surprises and anomalies. The book resents practical techniques for causal modeling and analytics that practitioners can apply to improve understanding of how choices affect probabilities of consequences and, based on this understanding, to recommend choices that are more likely to accomplish their intended objectives.The book begins with a survey of modern analytics methods, focusing mainly on techniques useful for decision, risk, and policy analysis. Chapter 2 introduces free in-browser software, including the Causal Analytics Toolkit (CAT) software, to enable readers to perform the analyses described and to apply modern analytics methods easily to their own data sets. Chapters 3 through 11 show how to apply causal analytics and risk analytics to practical risk analysis challenges, mainly related to public and occupational health risks from pathogens in food or from pollutants in air. Chapters 12 through 15 turn to broader questions of how to improve risk management decision-making by individuals, groups, organizations, institutions, and multi-generation societies with different cultures and norms for cooperation. These chapters examine organizational learning, community resilience, societal risk management, and intergenerational collaboration and justice in managing risks..

Business & Economics

Drug Discovery Targeting Drug-Resistant Bacteria | Prashant Kesharwani,Sidharth Chopra,Arunava Dasgupta

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Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war.